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ESWA
2006
122views more  ESWA 2006»
13 years 8 months ago
Transmembrane segments prediction and understanding using support vector machine and decision tree
In recent years, there have been many studies focusing on improving the accuracy of prediction of transmembrane segments, and many significant results have been achieved. In spite...
Jieyue He, Hae-Jin Hu, Robert W. Harrison, Phang C...
BIOINFORMATICS
2011
13 years 8 days ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
CSB
2004
IEEE
146views Bioinformatics» more  CSB 2004»
14 years 12 days ago
Automated Protein Classification Using Consensus Decision
We propose a novel technique for automatically generating the SCOP classification of a protein structure with high accuracy. High accuracy is achieved by combining the decisions o...
Tolga Can, Orhan Çamoglu, Ambuj K. Singh, Y...
NAR
2011
207views Computer Vision» more  NAR 2011»
12 years 11 months ago
PSORTdb - an expanded, auto-updated, user-friendly protein subcellular localization database for Bacteria and Archaea
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
Nancy Y. Yu, Matthew R. Laird, Cory Spencer, Fiona...
BMCBI
2010
113views more  BMCBI 2010»
13 years 8 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...