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BMCBI
2007
203views more  BMCBI 2007»
13 years 7 months ago
A Grid-based solution for management and analysis of microarrays in distributed experiments
Several systems have been presented in the last years in order to manage the complexity of large microarray experiments. Although good results have been achieved, most systems ten...
Ivan Porro, Livia Torterolo, Luca Corradi, Marco F...
BMCBI
2007
138views more  BMCBI 2007»
13 years 7 months ago
A systematic approach to detecting transcription factors in response to environmental stresses
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
BMCBI
2002
214views more  BMCBI 2002»
13 years 7 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2010
167views more  BMCBI 2010»
13 years 8 months ago
Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
BMCBI
2006
110views more  BMCBI 2006»
13 years 7 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen