31 search results - page 4 / 7 » A New Approach for Gene Annotation Using Unambiguous Sequenc... |
BMCBI
2007
13 years 7 months ago
2007
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
BMCBI
2005
13 years 7 months ago
2005
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
BMCBI
2002
13 years 7 months ago
2002
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
BMCBI
2007
13 years 7 months ago
2007
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
BMCBI
2006
13 years 7 months ago
2006
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...