563 search results - page 17 / 113 » A New Approach to Protein Structure Mining and Alignment |
BMCBI
2010
13 years 6 months ago
2010
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
RECOMB
2009
Springer
14 years 7 months ago
2009
Springer
Collective behavior involving distally separate regions in a protein is known to widely affect its function. In this paper, we present an online approach to study and characterize ...
BMCBI
2007
13 years 6 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2005
13 years 6 months ago
2005
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
BMCBI
2010
13 years 6 months ago
2010
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...