The purpose of this paper is to evaluate the hypothesis that a systems biology approach can be developed such that a set of transcription factors, relevant to burn-induced inflamm...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Fra...
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
A considerable fraction of yeast gene promoters are bound by multiple transcription factors. To study the combinatorial interactions of multiple transcription factors is thus impor...