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BMCBI
2007
129views more  BMCBI 2007»
13 years 7 months ago
A novel approach to sequence validating protein expression clones with automated decision making
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
Elena Taycher, Andreas Rolfs, Yanhui Hu, Dongmei Z...
BMCBI
2007
135views more  BMCBI 2007»
13 years 7 months ago
DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput
Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian ...
BMCBI
2007
169views more  BMCBI 2007»
13 years 7 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2008
167views more  BMCBI 2008»
13 years 7 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
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