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» A factor analysis model for functional genomics
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BMCBI
2007
149views more  BMCBI 2007»
13 years 8 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
RECOMB
2009
Springer
14 years 8 months ago
Spatial Clustering of Multivariate Genomic and Epigenomic Information
The combination of fully sequence genomes and new technologies for high density arrays and ultra-rapid sequencing enables the mapping of generegulatory and epigenetics marks on a g...
Rami Jaschek, Amos Tanay
DAC
2000
ACM
14 years 9 months ago
On switch factor based analysis of coupled RC interconnects
We revisit a basic element of modern signal integrity analysis, the modeling of worst-case coupling capacitance effects within a switch factor (SF) based methodology. We show that...
Andrew B. Kahng, Sudhakar Muddu, Egino Sarto
BMCBI
2005
86views more  BMCBI 2005»
13 years 7 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
BMCBI
2011
13 years 3 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein