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» A graphical model for predicting protein molecular function
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NAR
2006
61views more  NAR 2006»
13 years 7 months ago
MAVL/StickWRLD: analyzing structural constraints using interpositional dependencies in biomolecular sequence alignments
The increasing availability of structurally aligned protein families has made it possible to use statistical methods to discover regions of interpositional dependenciesof residue ...
Hatice Gulcin Ozer, William C. Ray
EVOW
2012
Springer
12 years 3 months ago
Multiobjectivizing the HP Model for Protein Structure Prediction
Abstract. The hydrophobic-polar (HP) model for protein structure preabstracts the fact that hydrophobic interactions are a dominant force in the protein folding process. This model...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
RECOMB
2007
Springer
14 years 8 months ago
Free Energy Estimates of All-Atom Protein Structures Using Generalized Belief Propagation
We present a technique for approximating the free energy of protein structures using Generalized Belief Propagation (GBP). The accuracy and utility of these estimates are then demo...
Hetunandan Kamisetty, Eric P. Xing, Christopher Ja...
PAKDD
2005
ACM
180views Data Mining» more  PAKDD 2005»
14 years 1 months ago
Conditional Random Fields for Transmembrane Helix Prediction
Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Lior Lukov, Sanjay Chawla, W. Bret Church
BMCBI
2007
142views more  BMCBI 2007»
13 years 8 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...