The increasing availability of structurally aligned protein families has made it possible to use statistical methods to discover regions of interpositional dependenciesof residue ...
Abstract. The hydrophobic-polar (HP) model for protein structure preabstracts the fact that hydrophobic interactions are a dominant force in the protein folding process. This model...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
We present a technique for approximating the free energy of protein structures using Generalized Belief Propagation (GBP). The accuracy and utility of these estimates are then demo...
Hetunandan Kamisetty, Eric P. Xing, Christopher Ja...
Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...