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BMCBI
2008
115views more  BMCBI 2008»
13 years 8 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2005
148views more  BMCBI 2005»
13 years 8 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
BMCBI
2006
213views more  BMCBI 2006»
13 years 8 months ago
CoXpress: differential co-expression in gene expression data
Background: Traditional methods of analysing gene expression data often include a statistical test to find differentially expressed genes, or use of a clustering algorithm to find...
Michael Watson
APBC
2004
107views Bioinformatics» more  APBC 2004»
13 years 9 months ago
An Empirical Bayes Adjustment to Multiple p-values for the Detection of Differentially Expressed Genes in Microarray Experiments
In recent microarray experiments thousands of gene expressions are simultaneously tested in comparing samples (e.g., tissue types or experimental conditions). Application of a sta...
Somnath Datta, Susmita Datta