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» Adversarial Sequence Prediction
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PRIB
2010
Springer
123views Bioinformatics» more  PRIB 2010»
13 years 8 months ago
Machine Learning Study of DNA Binding by Transcription Factors from the LacI Family
We studied 1372 LacI-family transcription factors and their 4484 DNA binding sites using machine learning algorithms and feature selection techniques. The Naive Bayes classifier a...
Gennady G. Fedonin, Mikhail S. Gelfand
RECOMB
2006
Springer
14 years 10 months ago
Detecting MicroRNA Targets by Linking Sequence, MicroRNA and Gene Expression Data
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
Jim C. Huang, Quaid Morris, Brendan J. Frey
ISMB
1994
13 years 11 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
JCB
2007
130views more  JCB 2007»
13 years 9 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2007
144views more  BMCBI 2007»
13 years 9 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...