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FOCS
2008
IEEE
13 years 9 months ago
Minimizing Movement in Mobile Facility Location Problems
In the mobile facility location problem, which is a variant of the classical Uncapacitated Facility Location and kMedian problems, each facility and client is assigned to a start ...
Zachary Friggstad, Mohammad R. Salavatipour
BMCBI
2010
130views more  BMCBI 2010»
13 years 9 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
155views more  BMCBI 2010»
13 years 9 months ago
A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
BMCBI
2007
144views more  BMCBI 2007»
13 years 8 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
Lower bounds on multiple sequence alignment using exact 3-way alignment
Background: Multiple sequence alignment is fundamental. Exponential growth in computation time appears to be inevitable when an optimal alignment is required for many sequences. E...
Charles J. Colbourn, Sudhir Kumar