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» Alignments of RNA Structures
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NAR
2010
119views more  NAR 2010»
13 years 2 months ago
3V: cavity, channel and cleft volume calculator and extractor
As larger macromolecular structures become available, there is a growing need to understand their `internal' volumes--such as deep clefts, channels and cavities--as these oft...
Neil Voss, Mark Gerstein
BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...
RECOMB
2006
Springer
14 years 8 months ago
CONTRAlign: Discriminative Training for Protein Sequence Alignment
In this paper, we present CONTRAlign, an extensible and fully automatic framework for parameter learning and protein pairwise sequence alignment using pair conditional random field...
Chuong B. Do, Samuel S. Gross, Serafim Batzoglou
ESWS
2008
Springer
13 years 9 months ago
Two Variations on Ontology Alignment Evaluation: Methodological Issues
Evaluation of ontology alignments is in practice done in two ways: (1) assessing individual correspondences and (2) comparing the alignment to a reference alignment. However, this ...
Laura Hollink, Mark van Assem, Shenghui Wang, Anto...
BMCBI
2004
141views more  BMCBI 2004»
13 years 7 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin