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» Analyzing time series gene expression data
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BIOINFORMATICS
2005
151views more  BIOINFORMATICS 2005»
13 years 7 months ago
Differential and trajectory methods for time course gene expression data
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...
Yulan Liang, Bamidele Tayo, Xueya Cai, Arpad Kelem...
BMCBI
2010
193views more  BMCBI 2010»
13 years 7 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
NAR
2010
189views more  NAR 2010»
13 years 2 months ago
Serial Expression Analysis: a web tool for the analysis of serial gene expression data
Serial transcriptomics experiments investigate the dynamics of gene expression changes associated with a quantitative variable such as time or dosage. The statistical analysis of ...
María José Nueda, José Carbon...
CIBCB
2009
IEEE
13 years 8 months ago
Steady-state analysis of genetic regulatory networks modeled by nonlinear ordinary differential equations
Although Ordinary Differential Equations (ODEs) have been used to model Genetic Regulatory Networks (GRNs) in many previous works, their steady-state behaviors are not well studied...
Haixin Wang, Lijun Qian, Edward R. Dougherty
GECCO
2004
Springer
132views Optimization» more  GECCO 2004»
14 years 28 days ago
Optimizing Topology and Parameters of Gene Regulatory Network Models from Time-Series Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. Different approaches to infer the dependencies of gene r...
Christian Spieth, Felix Streichert, Nora Speer, An...