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JCB
2007
130views more  JCB 2007»
13 years 7 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2004
174views more  BMCBI 2004»
13 years 7 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
BMCBI
2002
147views more  BMCBI 2002»
13 years 7 months ago
Expression profiling of human renal carcinomas with functional taxonomic analysis
Background: Molecular characterization has contributed to the understanding of the inception, progression, treatment and prognosis of cancer. Nucleic acid array-based technologies...
Michael A. Gieseg, Theresa Cody, Michael Z. Man, S...
IDA
2002
Springer
13 years 7 months ago
Evolutionary model selection in unsupervised learning
Feature subset selection is important not only for the insight gained from determining relevant modeling variables but also for the improved understandability, scalability, and pos...
YongSeog Kim, W. Nick Street, Filippo Menczer
NAR
1998
121views more  NAR 1998»
13 years 7 months ago
The Nuclear Receptor Resource: a growing family
Last year, the original Glucocorticoid Receptor Resource expanded into a comprehensive project: the Nuclear Receptor Resource (NRR, http://nrr.georgetown.edu/nrr/ nrr.html ). The ...
Elisabeth Martinez, David D. Moore, Evan Keller, D...