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BMCBI
2007
2007
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
13 years 7 months ago
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
BMCBI
2008
13 years 7 months ago
2008
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
BMCBI
2007
13 years 7 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
BMCBI
2007
13 years 7 months ago
2007
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
BMCBI
2008
13 years 7 months ago
2008
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...