Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...