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BMCBI
2008
146views more  BMCBI 2008»
13 years 8 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
BMCBI
2004
123views more  BMCBI 2004»
13 years 8 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
BMCBI
2007
116views more  BMCBI 2007»
13 years 8 months ago
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
César L. Avila, Viviana A. Rapisarda, Ricar...
CIBCB
2005
IEEE
14 years 2 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
NAR
2011
257views Computer Vision» more  NAR 2011»
12 years 11 months ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...