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BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
BMCBI
2010
127views more  BMCBI 2010»
13 years 9 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2010
134views more  BMCBI 2010»
13 years 9 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
RECOMB
2007
Springer
14 years 9 months ago
A Feature-Based Approach to Modeling Protein-DNA Interactions
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
Eilon Sharon, Eran Segal
BMCBI
2008
101views more  BMCBI 2008»
13 years 9 months ago
Prediction of glycosylation sites using random forests
Background: Post translational modifications (PTMs) occur in the vast majority of proteins and are essential for function. Prediction of the sequence location of PTMs enhances the...
Stephen E. Hamby, Jonathan D. Hirst