Sciweavers

17 search results - page 1 / 4
» Computing the Drift of Mutant Genes
Sort
View
CSC
2006
13 years 8 months ago
Computing the Drift of Mutant Genes
- We develop a numerical scheme for computing the solution of a generalized version of Fisher's equation. The main idea is to use a modi ed Crank-Nicolson method in order to c...
Miguel Olmos-Gomez, Merced Arriaga-Gutierrez, Vali...
BMCBI
2007
155views more  BMCBI 2007»
13 years 7 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
ISMB
2007
13 years 9 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
SNPD
2004
13 years 8 months ago
Prediction of Protein Dispensability through Integrated Analysis of Multiple-Source High-Throughput Data
Protein dispensability is fundamental to understanding of gene function and evolution. It is usually studied at the individual gene phenotype level. Recent advances in generating ...
Yu Chen, Dong Xu
NAR
2011
227views Computer Vision» more  NAR 2011»
13 years 2 months ago
VnD: a structure-centric database of disease-related SNPs and drugs
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
Jin Ok Yang, Sangho Oh, Gunhwan Ko, Seong-Jin Park...