Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...
Michael Hackenberg, Guillermo Barturen, José...
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
Ulf Schaefer, Sebastian Schmeier, Vladimir B. Baji...
The techniques described in this paper allow multiscale photon-limited image reconstruction methods to be implemented with significantly less computational complexity than previou...
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
In the context of physical synthesis, large-scale standard-cell placement algorithms must facilitate incremental changes to layout, both local and global. In particular, flexible...