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RECOMB
2009
Springer
14 years 8 months ago
Shared Peptides in Mass Spectrometry Based Protein Quantification
In analyzing the proteome using mass spectrometry, the mass values help identify the molecules, and the intensities help quantify them, relative to their abundance in other sample...
Banu Dost, Nuno Bandeira, Xiangqian Li, Zhouxin Sh...
APBC
2004
107views Bioinformatics» more  APBC 2004»
13 years 9 months ago
An Empirical Bayes Adjustment to Multiple p-values for the Detection of Differentially Expressed Genes in Microarray Experiments
In recent microarray experiments thousands of gene expressions are simultaneously tested in comparing samples (e.g., tissue types or experimental conditions). Application of a sta...
Somnath Datta, Susmita Datta
NA
2010
85views more  NA 2010»
13 years 6 months ago
The reliability/cost trade-off for a class of ODE solvers
In the numerical solution of ODEs, it is now possible to develop efficient techniques that will deliver approximate solutions that are piecewise polynomials. The resulting methods...
Wayne H. Enright, Li Yan
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
Prediction of RNA secondary structure by maximizing pseudo-expected accuracy
Background: Recent studies have revealed the importance of considering the entire distribution of possible secondary structures in RNA secondary structure predictions; therefore, ...
Michiaki Hamada, Kengo Sato, Kiyoshi Asai