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» Current approaches to gene regulatory network modelling
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BMCBI
2007
136views more  BMCBI 2007»
13 years 8 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
BLISS: biding site level identification of shared signal-modules in DNA regulatory sequences
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...
Hailong Meng, Arunava Banerjee, Lei Zhou
IMSCCS
2006
IEEE
14 years 2 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMEI
2008
IEEE
14 years 2 months ago
Using Phylogenetic Relationships to Improve the Inference of Transcriptional Regulatory Networks
Inferring transcriptional regulatory networks from geneexpression data remains a challenging problem, in part because of the noisy nature of the data and the lack of strong networ...
Xiuwei Zhang, Maryam Zaheri, Bernard M. E. Moret
ESWA
2006
103views more  ESWA 2006»
13 years 8 months ago
Model gene network by semi-fixed Bayesian network
Gene networks describe functional pathways in a given cell or tissue, representing processes such as metabolism, gene expression regulation, and protein or RNA transport. Thus, le...
Tie-Fei Liu, Wing-Kin Sung, Ankush Mittal