854 search results - page 58 / 171 » Current approaches to gene regulatory network modelling |
BMCBI
2008
13 years 8 months ago
2008
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
BMCBI
2006
13 years 8 months ago
2006
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
BMCBI
2010
13 years 8 months ago
2010
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
RECOMB
2007
Springer
14 years 8 months ago
2007
Springer
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
RECOMB
2010
Springer
13 years 10 months ago
2010
Springer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...