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BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
CSB
2003
IEEE
124views Bioinformatics» more  CSB 2003»
14 years 1 months ago
SMASHing regulatory sites in DNA by human
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...
BMCBI
2007
158views more  BMCBI 2007»
13 years 8 months ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
VLSID
2002
IEEE
106views VLSI» more  VLSID 2002»
14 years 8 months ago
SWASAD: An ASIC Design for High Speed DNA Sequence Matching
This paper presents the Smith and Waterman Algorithm-Specific ASIC Design (SWASAD) project. This is a hardware solution that implements the S&W algorithm.. The SWASAD is an imp...
Tony Han, Sri Parameswaran
TSMC
2008
93views more  TSMC 2008»
13 years 8 months ago
Selection of DNA Markers
Given a genome, i.e., a long string over a fixed finite alphabet, the problem is to find short (dis)similar substrings. This computationally intensive task has many biological appl...
Hendrik Jan Hoogeboom, Walter A. Kosters, Jeroen F...