Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
Nancy Y. Yu, Matthew R. Laird, Cory Spencer, Fiona...
LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New ...
Alexander Mehrle, Heiko Rosenfelder, Ingo Schupp, ...
Massively parallel sequencing technologies continue to alter the study of human genetics. As the cost of sequencing declines, next-generation sequencing (NGS) instruments and data...
Daniel C. Koboldt, Li Ding, Elaine R. Mardis, Rich...
We propose a new method to build persistent suffix trees for indexing the genomic data. Our algorithm DiGeST (Disk-Based Genomic Suffix Tree) improves significantly over previous ...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...