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» Data-adaptive test statistics for microarray data
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BMCBI
2007
165views more  BMCBI 2007»
13 years 7 months ago
TagSmart: analysis and visualization for yeast mutant fitness data measured by tag microarrays
Background: A nearly complete collection of gene-deletion mutants (96% of annotated open reading frames) of the yeast Saccharomyces cerevisiae has been systematically constructed....
Chulyun Kim, Sangkyum Kim, Russell Dorer, Dan Xie,...
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi
APBC
2004
107views Bioinformatics» more  APBC 2004»
13 years 8 months ago
An Empirical Bayes Adjustment to Multiple p-values for the Detection of Differentially Expressed Genes in Microarray Experiments
In recent microarray experiments thousands of gene expressions are simultaneously tested in comparing samples (e.g., tissue types or experimental conditions). Application of a sta...
Somnath Datta, Susmita Datta
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2008
107views more  BMCBI 2008»
13 years 7 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....