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BMCBI
2007
2007
Application of amino acid occurrence for discriminating different folding types of globular proteins
13 years 10 months ago
Background: Predicting the three-dimensional structure of a protein from its amino acid sequence is a long-standing goal in computational/molecular biology. The discrimination of ...
BMCBI
2007
13 years 10 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
BIOINFORMATICS
2006
13 years 10 months ago
2006
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
BMCBI
2006
13 years 10 months ago
2006
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
BMCBI
2006
13 years 10 months ago
2006
Background: Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These E...