Microfluidics-based biochips offer exciting possibilities for highthroughput sequencing, parallel immunoassays, blood chemistry for clinical diagnostics, DNA sequencing, and envir...
Hidden Markov Models (HMMs) are an useful and widely utilized approach to the modeling of data sequences. One of the problems related to this technique is finding the optimal stru...
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
BLASTn is a ubiquitous tool used for large scale DNA analysis. Detailed profiling tests reveal that the most computationally intensive sections of the BLASTn algorithm are the sc...