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BMCBI
2006
104views more  BMCBI 2006»
13 years 7 months ago
MANET: tracing evolution of protein architecture in metabolic networks
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
BCB
2010
175views Bioinformatics» more  BCB 2010»
13 years 2 months ago
Gene set analysis using principal components
We present a new method for identifying gene sets associated with labeled samples, where the labels can be case versus control, or genotype differences. Existing approaches to thi...
Isa Kemal Pakatci, Wei Wang, Leonard McMillan
NAR
2006
87views more  NAR 2006»
13 years 7 months ago
From genomics to chemical genomics: new developments in KEGG
The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interacti...
Minoru Kanehisa, Susumu Goto, Masahiro Hattori, Ki...
IJCNN
2006
IEEE
14 years 1 months ago
Comparing Kernels for Predicting Protein Binding Sites from Amino Acid Sequence
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
Feihong Wu