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BMCBI
2010
150views more  BMCBI 2010»
13 years 7 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BIOINFORMATICS
2006
134views more  BIOINFORMATICS 2006»
13 years 7 months ago
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
Mahender Kumar Singh, Shilpy Srivastava, G. P. S. ...
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
IISWC
2008
IEEE
14 years 2 months ago
Accelerating multi-core processor design space evaluation using automatic multi-threaded workload synthesis
The design and evaluation of microprocessor architectures is a difficult and time-consuming task. Although small, handcoded microbenchmarks can be used to accelerate performance e...
Clay Hughes, Tao Li