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» Differential Algebra and System Modeling in Cellular Biology
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RECOMB
2006
Springer
14 years 8 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
BMCBI
2010
183views more  BMCBI 2010»
13 years 5 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
FMSB
2008
129views Formal Methods» more  FMSB 2008»
13 years 9 months ago
Rule-Based Modelling, Symmetries, Refinements
Rule-based modelling is particularly effective for handling the highly combinatorial aspects of cellular signalling. The dynamics is described in terms of interactions between part...
Vincent Danos, Jérôme Feret, Walter F...
MICCAI
2005
Springer
14 years 8 months ago
Hybrid Segmentation Framework for Tissue Images Containing Gene Expression Data
Associating speci c gene activity with speci c functional locations in the brain anatomy results in a greater understanding of the role of the gene's products. To perform such...
Musodiq Bello, Tao Ju, Joe D. Warren, James Carson...
CSB
2005
IEEE
128views Bioinformatics» more  CSB 2005»
13 years 9 months ago
Application of a Generalized MWC Model for the Mathematical Simulation of Metabolic Pathways Regulated by Allosteric Enzymes
In our effort to elucidate the systems biology of the model organism, Escherichia coli, we have developed a mathematical model that simulates the allosteric regulation for threoni...
Tarek S. Najdi, Chin-Rang Yang, Bruce E. Shapiro, ...