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BMCBI
2008
201views more  BMCBI 2008»
13 years 8 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2007
148views more  BMCBI 2007»
13 years 8 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
BMCBI
2007
144views more  BMCBI 2007»
13 years 8 months ago
Gene analogue finder: a GRID solution for finding functionally analogous gene products
Background: To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in a...
Angelica Tulipano, Giacinto Donvito, Flavio Licciu...
BMCBI
2007
155views more  BMCBI 2007»
13 years 8 months ago
ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites
Background: In the last decade, techniques were established for the large scale genome-wide analysis of proteins, RNA, and metabolites, and database solutions have been developed ...
Jan Hummel, Michaela Niemann, Stefanie Wienkoop, W...
JCB
2006
123views more  JCB 2006»
13 years 8 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange