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BMCBI
2008
186views more  BMCBI 2008»
13 years 8 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2007
120views more  BMCBI 2007»
13 years 8 months ago
Recognition of interferon-inducible sites, promoters, and enhancers
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...
Elena A. Ananko, Yury V. Kondrakhin, Tatyana I. Me...
BMCBI
2008
90views more  BMCBI 2008»
13 years 8 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
BMCBI
2007
81views more  BMCBI 2007»
13 years 8 months ago
PADB : Published Association Database
Background: Although molecular pathway information and the International HapMap Project data can help biomedical researchers to investigate the aetiology of complex diseases more ...
Hwanseok Rhee, Jin-Sung Lee
BMCBI
2008
98views more  BMCBI 2008»
13 years 8 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
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