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BMCBI
2006
88views more  BMCBI 2006»
13 years 7 months ago
Effect of various normalization methods on Applied Biosystems expression array system data
Background: DNA microarray technology provides a powerful tool for characterizing gene expression on a genome scale. While the technology has been widely used in discovery-based m...
Catalin C. Barbacioru, Yulei Wang, Roger D. Canale...
BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
BMCBI
2002
195views more  BMCBI 2002»
13 years 7 months ago
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
Background: A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expressio...
Junbai Wang, Jan Delabie, Hans Christian Aasheim, ...