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» Empirical Analysis of Rate Limiting Mechanisms
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CANDC
2006
ACM
13 years 7 months ago
Why substrate depletion has apparent first-order kinetics in enzymatic digestion
A number of enzyme digestion assays show apparent first-order kinetics of reactant depletion. There are four possible explanations of this phenomenon: (i) the reaction is dominate...
Jeyaraman Srividhya, Santiago Schnell
BMCBI
2010
142views more  BMCBI 2010»
13 years 4 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
BMCBI
2004
126views more  BMCBI 2004»
13 years 7 months ago
Visualization and analysis of microarray and gene ontology data with treemaps
Background: The increasing complexity of genomic data presents several challenges for biologists. Limited computer monitor views of data complexity and the dynamic nature of data ...
Eric H. Baehrecke, Niem Dang, Ketan Babaria, Ben S...
COLT
2007
Springer
14 years 1 months ago
Minimax Bounds for Active Learning
This paper analyzes the potential advantages and theoretical challenges of “active learning” algorithms. Active learning involves sequential sampling procedures that use infor...
Rui Castro, Robert D. Nowak
ICCD
2008
IEEE
202views Hardware» more  ICCD 2008»
14 years 4 months ago
CrashTest: A fast high-fidelity FPGA-based resiliency analysis framework
— Extreme scaling practices in silicon technology are quickly leading to integrated circuit components with limited reliability, where phenomena such as early-transistor failures...
Andrea Pellegrini, Kypros Constantinides, Dan Zhan...