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» Enhanced pClustering and Its Applications to Gene Expression...
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BMCBI
2007
120views more  BMCBI 2007»
13 years 7 months ago
Recognition of interferon-inducible sites, promoters, and enhancers
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...
Elena A. Ananko, Yury V. Kondrakhin, Tatyana I. Me...
BMCBI
2008
98views more  BMCBI 2008»
13 years 7 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2010
214views more  BMCBI 2010»
13 years 7 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2008
125views more  BMCBI 2008»
13 years 7 months ago
Exploration and visualization of gene expression with neuroanatomy in the adult mouse brain
Background: Spatially mapped large scale gene expression databases enable quantitative comparison of data measurements across genes, anatomy, and phenotype. In most ongoing effort...
Christopher Lau, Lydia Ng, Carol Thompson, Sayan D...
BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Dynamic modeling of cis-regulatory circuits and gene expression prediction via cross-gene identification
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...