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» Estimating Genome Reversal Distance by Genetic Algorithm
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JEA
2008
97views more  JEA 2008»
13 years 7 months ago
Approximating the true evolutionary distance between two genomes
As more and more genomes are sequenced, evolutionary biologists are becoming increasingly interested in evolution at the level of whole genomes, in scenarios in which the genome e...
Krister M. Swenson, Mark Marron, Joel V. Earnest-D...
BMCBI
2007
138views more  BMCBI 2007»
13 years 7 months ago
Fast computation of distance estimators
Background: Some distance methods are among the most commonly used methods for reconstructing phylogenetic trees from sequence data. The input to a distance method is a distance m...
Isaac Elias, Jens Lagergren
RECOMB
2009
Springer
14 years 2 months ago
Rearrangement Models and Single-Cut Operations
Abstract. There have been many widely used genome rearrangement models, such as reversals, HannenhalliPevzner, and double-cut and join. Though each one can be precisely defined, t...
Paul Medvedev, Jens Stoye
BMCBI
2005
93views more  BMCBI 2005»
13 years 7 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...