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» Evolution of Biological Complexity
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BMCBI
2011
13 years 1 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
JCC
2011
154views more  JCC 2011»
13 years 24 days ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
JCC
2011
109views more  JCC 2011»
13 years 24 days ago
VoteDock: Consensus docking method for prediction of protein-ligand interactions
: Molecular recognition plays a fundamental role in all biological processes, and that is why great efforts have been made to understand and predict protein–ligand interactions. ...
Dariusz Plewczynski, Michal Lazniewski, Marcin von...
NAR
2011
209views Computer Vision» more  NAR 2011»
13 years 23 days ago
REPAIRtoire - a database of DNA repair pathways
REPAIRtoire is the first comprehensive database resource for systems biology of DNA damage and repair. The database collects and organizes the following types of information: (i) ...
Kaja Milanowska, Joanna Krwawicz, Grzegorz Papaj, ...
BMCBI
2007
217views more  BMCBI 2007»
13 years 10 months ago
OntologyWidget - a reusable, embeddable widget for easily locating ontology terms
Background: Biomedical ontologies are being widely used to annotate biological data in a computer-accessible, consistent and well-defined manner. However, due to their size and co...
Catherine Beauheim, Farrell Wymore, Michael Nitzbe...