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» Extensions to gene set enrichment
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CSB
2004
IEEE
152views Bioinformatics» more  CSB 2004»
14 years 1 months ago
Comparative Analysis of Gene Sets in the Gene Ontology Space under the Multiple Hypothesis Testing Framework
The Gene Ontology (GO) resource can be used as a powerful tool to uncover the properties shared among, and specific to, a list of genes produced by high-throughput functional geno...
Sheng Zhong, Lu Tian, Cheng Li, Kai-Florian Storch...
BMCBI
2008
160views more  BMCBI 2008»
13 years 10 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
BMCBI
2007
157views more  BMCBI 2007»
13 years 10 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
NAR
2010
123views more  NAR 2010»
13 years 4 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
CINQ
2004
Springer
116views Database» more  CINQ 2004»
14 years 1 months ago
Contribution to Gene Expression Data Analysis by Means of Set Pattern Mining
Abstract. One of the exciting scientific challenges in functional genomics concerns the discovery of biologically relevant patterns from gene expression data. For instance, it is e...
Ruggero G. Pensa, Jérémy Besson, C&e...