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» Extracting active pathways from gene expression data
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BMCBI
2005
126views more  BMCBI 2005»
13 years 8 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene
BMCBI
2007
151views more  BMCBI 2007»
13 years 9 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
NAR
2011
191views Computer Vision» more  NAR 2011»
12 years 11 months ago
ConsensusPathDB: toward a more complete picture of cell biology
ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabol...
Atanas Kamburov, Konstantin Pentchev, Hanna Galick...
BMCBI
2010
181views more  BMCBI 2010»
13 years 9 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
BMCBI
2006
179views more  BMCBI 2006»
13 years 9 months ago
Accurate and unambiguous tag-to-gene mapping in serial analysis of gene expression
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
Rodrigo Malig, Cristian Varela, Eduardo Agosin, Fr...