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» Finding approximate tandem repeats in genomic sequences
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IPPS
2010
IEEE
13 years 5 months ago
pFANGS: Parallel high speed sequence mapping for Next Generation 454-roche Sequencing reads
Millions of DNA sequences (reads) are generated by Next Generation Sequencing machines everyday. There is a need for high performance algorithms to map these sequences to the refer...
Sanchit Misra, Ramanathan Narayanan, Wei-keng Liao...
RECOMB
2006
Springer
14 years 8 months ago
Alignment Statistics for Long-Range Correlated Genomic Sequences
It is well known that the base composition along eukaryotic genomes is long-range correlated. Here, we investigate the effect of such long-range correlations on alignment score sta...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
BMCBI
2007
154views more  BMCBI 2007»
13 years 8 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
JDA
2008
122views more  JDA 2008»
13 years 7 months ago
An approximation algorithm for sorting by reversals and transpositions
Abstract. Genome rearrangement algorithms are powerful tools to analyze gene orders in molecular evolution. Analysis of genomes evolving by reversals and transpositions leads to a ...
Atif Rahman, Swakkhar Shatabda, Masud Hasan