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ALMOB
2006
109views more  ALMOB 2006»
13 years 9 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BIOINFORMATICS
2006
92views more  BIOINFORMATICS 2006»
13 years 9 months ago
What should be expected from feature selection in small-sample settings
Motivation: High-throughput technologies for rapid measurement of vast numbers of biological variables offer the potential for highly discriminatory diagnosis and prognosis; howev...
Chao Sima, Edward R. Dougherty
BMCBI
2006
126views more  BMCBI 2006»
13 years 9 months ago
Effect of data normalization on fuzzy clustering of DNA microarray data
Background: Microarray technology has made it possible to simultaneously measure the expression levels of large numbers of genes in a short time. Gene expression data is informati...
Seo Young Kim, Jae Won Lee, Jong Sung Bae
BMCBI
2006
152views more  BMCBI 2006»
13 years 9 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...
BMCBI
2006
127views more  BMCBI 2006»
13 years 9 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...