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NAR
2006
85views more  NAR 2006»
13 years 8 months ago
WormBase: better software, richer content
WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biol...
Erich M. Schwarz, Igor Antoshechkin, Carol Bastian...
BMCBI
2007
166views more  BMCBI 2007»
13 years 8 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
IHI
2012
370views Healthcare» more  IHI 2012»
12 years 4 months ago
FUSE: a system for data-driven multi-level functional summarization of protein interaction networks
Despite recent progress in high-throughput experimental studies, systems level visualization and analysis of large protein interaction networks (ppi) remains a challenging task, g...
Boon-Siew Seah, Sourav S. Bhowmick, Charles Forbes...
BMCBI
2010
119views more  BMCBI 2010»
13 years 8 months ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
BMCBI
2006
105views more  BMCBI 2006»
13 years 8 months ago
Integrative investigation of metabolic and transcriptomic data
Background: New analysis methods are being developed to integrate data from transcriptome, proteome, interactome, metabolome, and other investigative approaches. At the same time,...
Pinar Pir, Betül Kirdar, Andrew Hayes, Z. Ils...