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BMCBI
2006
199views more  BMCBI 2006»
13 years 8 months ago
PageMan: An interactive ontology tool to generate, display, and annotate overview graphs for profiling experiments
Background: Microarray technology has become a widely accepted and standardized tool in biology. The first microarray data analysis programs were developed to support pair-wise co...
Björn Usadel, Axel Nagel, Dirk Steinhauser, Y...
ALMOB
2006
106views more  ALMOB 2006»
13 years 8 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
BMCBI
2006
104views more  BMCBI 2006»
13 years 8 months ago
MANET: tracing evolution of protein architecture in metabolic networks
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2006
129views more  BMCBI 2006»
13 years 8 months ago
EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
Laila A. Nahum, Matthew T. Reynolds, Zhengyuan O. ...