231 search results - page 5 / 47 » Functional topology in a network of protein interactions |
BMCBI
2008
13 years 7 months ago
2008
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
JMLR
2010
2010
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
13 years 2 months ago
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
BMCBI
2010
13 years 7 months ago
2010
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
ALMOB
2006
13 years 7 months ago
2006
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
BMCBI
2005
13 years 7 months ago
2005
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...