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BMCBI
2007
148views more  BMCBI 2007»
13 years 8 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
IADIS
2008
13 years 9 months ago
Sisa: Seeded Iterative Signature Algorithm for Biclustering Gene Expression Data
One approach to reduce the complexity of the task in the analysis of large scale genome-wide expression is to group the genes showing similar expression patterns into what are cal...
Neelima Gupta, Seema Aggarwal
CEC
2008
IEEE
13 years 8 months ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
GECCO
2004
Springer
169views Optimization» more  GECCO 2004»
14 years 1 months ago
Genetic Programming Neural Networks as a Bioinformatics Tool for Human Genetics
The identification of genes that influence the risk of common, complex diseases primarily through interactions with other genes and environmental factors remains a statistical and ...
Marylyn D. Ritchie, Christopher S. Coffey, Jason H...