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» Gene finding in novel genomes
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BMCBI
2011
13 years 3 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
NAR
2011
208views Computer Vision» more  NAR 2011»
12 years 11 months ago
CaSNP: a database for interrogating copy number alterations of cancer genome from SNP array data
Cancer is known to have abundant copy number alterations (CNAs) that greatly contribute to its pathogenesis and progression. Investigation of CNA regions could potentially help id...
Qingyi Cao, Meng Zhou, Xujun Wang, Clifford A. Mey...
TCBB
2010
106views more  TCBB 2010»
13 years 6 months ago
Predicting Novel Human Gene Ontology Annotations Using Semantic Analysis
—The correct interpretation of many molecular biology experiments depends in an essential way on the accuracy and consistency of the existing annotation databases. Such databases...
Bogdan Done, Purvesh Khatri, Arina Done, Sorin Dra...
BMCBI
2002
128views more  BMCBI 2002»
13 years 7 months ago
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in euka
Background: Gene regulation in eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding regi...
Michele Caselle, Ferdinando Di Cunto, Paolo Prover...
SOFTCO
2004
Springer
14 years 1 months ago
MultiNNProm: A Multi-Classifier System for Finding Genes
The computational identification of genes in DNA sequences has become an issue of crucial importance due to the large number of DNA molecules being currently sequenced. We present ...
Romesh Ranawana, Vasile Palade