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» Gene functional classification from heterogeneous data
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BMCBI
2005
105views more  BMCBI 2005»
15 years 3 months ago
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
151
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BMCBI
2011
14 years 7 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
168
Voted
NAR
2011
225views Computer Vision» more  NAR 2011»
14 years 6 months ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
110
Voted
KDD
2004
ACM
126views Data Mining» more  KDD 2004»
16 years 4 months ago
Turning CARTwheels: an alternating algorithm for mining redescriptions
We present an unusual algorithm involving classification trees-CARTwheels--where two trees are grown in opposite directions so that they are joined at their leaves. This approach ...
Naren Ramakrishnan, Deept Kumar, Bud Mishra, Malco...
109
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RECOMB
2008
Springer
16 years 4 months ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...