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» Genetic Algorithms for Protein Threading
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JCB
2006
114views more  JCB 2006»
13 years 7 months ago
A General Modeling Strategy for Gene Regulatory Networks with Stochastic Dynamics
A stochastic genetic toggle switch model that consists of two identical, mutually repressive genes is built using the Gillespie algorithm with time delays as an example of a simpl...
Andre Ribeiro, Rui Zhu, Stuart A. Kauffman
BMCBI
2007
186views more  BMCBI 2007»
13 years 7 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
CIKM
2005
Springer
14 years 1 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
BMCBI
2002
109views more  BMCBI 2002»
13 years 7 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue