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SAC
2003
ACM
14 years 2 months ago
A Markov Random Field Model of Microarray Gridding
DNA microarray hybridisation is a popular high throughput technique in academic as well as industrial functional genomics research. In this paper we present a new approach to auto...
Mathias Katzer, Franz Kummert, Gerhard Sagerer
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
NC
2008
13 years 8 months ago
How crystals that sense and respond to their environments could evolve
An enduring mystery in biology is how a physical entity simple enough to have arisen spontaneously could have evolved into the complex life seen on Earth today. Cairns-Smith has pr...
Rebecca Schulman, Erik Winfree
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
BMCBI
2007
115views more  BMCBI 2007»
13 years 8 months ago
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...