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BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
ICMLA
2010
13 years 6 months ago
Smoothing Gene Expression Using Biological Networks
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Yue Fan, Mark A. Kon, Shinuk Kim, Charles DeLisi
ACSC
2006
IEEE
14 years 2 months ago
Modelling layer 2 and layer 3 device bandwidths using B-node theory
Modern computer networks contain an amalgamation of devices and technologies, with the performance exhibited by each central to digital communications. Varieties of methods exist ...
S. Cikara, Stanislaw P. Maj, David T. Shaw
BMCBI
2005
223views more  BMCBI 2005»
13 years 8 months ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
BIOINFORMATICS
2011
13 years 3 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj